cmghjournal biocellvia

In this article, we show a critical role for differentially active T-cell subsets in visceral adipose tissue and liver in the pathogenesis of nonalcoholic steatohepatitis using multiple interventional experimental approaches in a high-fat, high- fructose diet mouse model.

juillet 6, 2020

Diet Reversal and Immune Modulation Show Key Role for Liver and Adipose Tissue T Cells in Murine Nonalcoholic Steatohepatitis

In this article, we show a critical role for differentially active T-cell subsets in visceral adipose tissue and liver in the pathogenesis of nonalcoholic steatohepatitis using […]
novembre 21, 2019
Toward a reader-independent IPF histological analysis

Toward a reader-independent IPF histological analysis

The quantification of histological features of Idiopathic Pulmonary Fibrosis (IPF) from human lung biopsies or rodent models relies upon a scoring evaluation established over thirty years […]
octobre 16, 2019
Toward a reader-independent NAFLD/NASH histological analysis

Toward a reader-independent NAFLD / NASH histological analysis

Pathologists currently use semi-quantitative image analysis based on scoring evaluation (NAS or SAF score) to assess NAFLD/NASH severity from human liver biopsies. This scoring evaluation is […]
octobre 1, 2019
Optimization of bleomycin concentration in IPF rodent model

Optimization of bleomycin concentration in IPF rodent model

Bleomycin (BLM) is the prevailing chemical treatment for inducing IPF in rodent models in view to study the efficacy of lead molecules. Literature data shows that […]

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