MORPHOQUANT-LIVER, AN AUTOMATED PATHOLOGIST-INDEPENDENT MORPHOMETRIC SOFTWARE, IDENTIFIED SIGNIFICANT DIFFERENCES BETWEEN STEATOTIC AND MASH LIVER BIOPSIES

Cindy Serdjebi1, Bastien Lepoivre1, Florine Chandes1, Linda Willis2, Yvon Julé1

1Biocellvia, Marseille, France cindy.serdjebi@biocellvia.com
2HistologiX, Innovation Building | BioCity Nottingham, Pennyfoot Street, Nottingham, NG1 1GF, United Kingdom

OBJECTIVES

▪ To assess the capability of MorphoQuant, an automated pathologist-independent morphometric software of digital pathology, to identify histological differences between steatotic liver disease (SLD) and metabolic dysfunction-associated steatohepatitis (MASH) liver biopsies through quantification of objective features.

▪ To compare MorphoQuant findings with the pathologist’s visual scoring.
▪ To assess the interest in quantifying Sonic Hedgehog (Shh) expression with digital pathology.

https://biocellvia.com/wp-content/uploads/2023/08/PosterAllReadout-ParisNASH_vCS.pdf