MORPHOMETRIC DIGITAL PATHOLOGY CONFIRMS CLINICAL TRANSLATABILITY FOR LANIFIBRANOR AND SEMAGLUTIDE IN BIOPSY-CONFIRMED GAN-DIO-NASH MICE

Cindy Serdjebi1, Florine Chandes1, Bastien Lepoivre1, Susanne E. Pors2, Michael Feigh2
1Biocellvia, Marseille, France cindy.serdjebi@biocellvia.com 2Gubra A/S, Hørsholm, Denmark

OBJECTIVES

▪ To assess Lanifibranor and Semaglutide effects on fibrosis and steatosis in the Gubra’s Amylin NASH (GAN) diet-induced obese (DIO) and biopsy-confirmed mouse model with advanced fibrosis using morphometric digital pathology.

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